Association of HLA and cytokine gene polymorphisms with idiopathic pulmonary fibrosis

human multidrug resistance 1 gene polymorphisms and idiopathic pulmonary fibrosis

background: for the first time we tested an association between the human multidrug resistance gene 1 (mdr1) polymorphisms (snps) and idiopathic pulmonary fibrosis (ipf). several mdr1 polymorphisms are associated with pathologies in which they modify the drug susceptibility and pharmacokinetics. materials and methods: we genotyped three mdr1 polymorphisms of 48 ipf patients and 100 control subj...

Author's response to reviews Title: Cytokine gene polymorphisms and serum cytokine levels in patients with idiopathic pulmonary fibrosis Authors:

Human Multidrug Resistance 1 gene polymorphisms and Idiopathic Pulmonary Fibrosis

BACKGROUND For the first time we tested an association between the human multidrug resistance gene 1 (MDR1) polymorphisms (SNPs) and idiopathic pulmonary fibrosis (IPF). Several MDR1 polymorphisms are associated with pathologies in which they modify the drug susceptibility and pharmacokinetics. MATERIALS AND METHODS We genotyped three MDR1 polymorphisms of 48 IPF patients and 100 control subj...

association of cytokine gene polymorphisms with bronchial asthma in macedonians

bronchial asthma is a multifactorial disease whereby both environmental and genetic factors contribute to its aetiology and/or clinical severity. the aim of this study was to examine the association of 22 cytokine gene polymorphism in the macedonian population with bronchial asthma (ba). the sample of the population comprised of 301 normal unrelated individuals and 74 patients with ba. cytokine...

Lack of Association of SP110 Gene Polymorphisms with Pulmonary Tuberculosis in Golestan Province, Iran

ABSTRACT           Background and Objectives: Mycobacterium tuberculosis is the causative agent of pulmonary tuberculosis, a main public health problem that results in 1.5 million deaths annually. A number of epidemiological studies suggested that host genetic factors could play a main role in susceptibility to tuberculosis infection. SP110 is an i...